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Crop Protection & Pesticides

Amistar Top (Azoxystrobin + Difenoconazole): Uses & Dose

Amistar Top is an advanced broad-spectrum combination fungicide manufactured by Syngenta, formulated with Azoxystrobin 18.2% and Difenoconazole 11.4% SC. By combining a strobilurin QoI inhibitor with a systemic triazole DMI, it provides preventative, curative, and antisporulant protection against blast, blight, and powdery mildew. Registered under CIBRC, it is widely used in paddy, chilli, tomato, and onion crops.

Last reviewed: 10 November 2026

Dual active chemistries and biochemical mode of action

Amistar Top pairs two complementary modes of action for broad-spectrum disease management.

Technical breakdown of constituents:

  • Azoxystrobin (18.2% SC): Strobilurin class (FRAC Group 11) that inhibits electron transfer at Complex III in fungal mitochondria, blocking ATP energy production.
  • Difenoconazole (11.4% SC): Triazole class (FRAC Group 3) that halts ergosterol biosynthesis, preventing fungal hyphae growth inside plant tissue.
  • Dual-phase protection: Azoxystrobin forms a preventive surface barrier preventing spore germination, while Difenoconazole provides systemic curative control.
  • Xylem mobility and translaminar action: Translocates acropetally through plant xylem vessels to protect new shoots and expanding foliage.
  • Physiological greening effect: Promotes prolonged green leaf area, improves nitrogen assimilation, and enhances overall crop vigour.

Target fungal diseases across approved crops

Amistar Top is approved by the Central Insecticides Board for destructive fungal pathogens:

Primary target diseases:

  • Paddy (Rice): Sheath blight (Rhizoctonia solani) and blast (Magnaporthe oryzae).
  • Chilli: Anthracnose fruit rot (dieback) and powdery mildew.
  • Tomato: Early blight (Alternaria solani) and Septoria leaf spot.
  • Onion: Purple blotch (Alternaria porri) and Stemphylium blight.
  • Maize: Turcicum leaf blight and Maydis leaf blight.

Application instructions, dosage and resistance care

Apply Amistar Top at approved CIBRC label rates (typically 1 ml per litre of water or 200 ml per acre in 200 litres of clean water) preventatively or at early infection onset. To protect against resistance, avoid more than two consecutive applications and alternate with multi-site contact protectants. Applicators should wear rubber gloves and a face mask, and strictly observe recommended pre-harvest waiting periods.

Official source

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Central Insecticides Board & Registration Committee (CIBRC) ↗

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Common questions

What is the technical composition of Amistar Top fungicide?

Amistar Top contains Azoxystrobin 18.2% plus Difenoconazole 11.4% formulated as a Suspension Concentrate (SC).

How does Amistar Top deliver both preventative and curative control?

Azoxystrobin prevents new fungal spores from germinating on the leaf surface, while Difenoconazole penetrates systemically to cure internal infections.

Which crops are officially registered for Amistar Top application?

It is officially registered for paddy (sheath blight, blast), chilli (anthracnose), tomato, onion, and maize.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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