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Crop Protection & Pesticides

Azoxystrobin + Difenoconazole SC: Dual-Action Fungicide

Azoxystrobin 18.2% + Difenoconazole 11.4% SC is a premix dual-action systemic fungicide widely registered in India for broad-spectrum disease management. By combining a strobilurin (Azoxystrobin, FRAC Group 11, inhibiting cellular respiration at the cytochrome bc1 complex) and a triazole (Difenoconazole, FRAC Group 3, disrupting ergosterol membrane synthesis), it delivers dual preventative and curative efficacy against ascomycetes, basidiomycetes, and deuteromycetes in crops such as rice, maize, chilli, and tomato.

Last reviewed: 10 November 2026

Key facts

From KisanPe's verified data. Confirm prices and doses with the seller, label or official source before acting.

Category
Fungicide
Mode of action
Systemic & Translaminar
Target crops
Chilly, Onion, Tomato, Paddy
Target pests
Purple Blotch, Anthracnose / Dieback, Early Blight, Sheath Blight

Chemical characteristics and complementary FRAC modes of action

Combining two complementary active ingredients from distinct chemical classes ensures robust fungicidal power while managing resistance.

  • Azoxystrobin (strobilurin, FRAC Group 11): Blocks electron transfer at the Qo site of complex III, shutting down ATP generation and spore germination.
  • Difenoconazole (triazole, FRAC Group 3): Inhibits sterol 14-alpha-demethylase, halting cell membrane synthesis and stopping mycelial development.
  • Translaminar and systemic movement: Moves through leaf tissue and translocates upward via plant xylem to protect newly expanding leaves.
  • Physiological greening effect: Promotes prolonged foliar chlorophyll retention and optimizes nitrogen uptake during grain formation.

Target crops and broad disease management spectrum

This premix fungicide formulation is approved under CIBRC regulations for multiple key field and commercial crops.

  • Rice (Paddy): Sheath blight (Rhizoctonia solani) and blast (Magnaporthe oryzae).
  • Chilli: Fruit rot (anthracnose dieback) and powdery mildew.
  • Maize: Maydis leaf blight and common rust.
  • Tomato: Early blight (Alternaria solani) and Septoria leaf spot.
  • Wheat: Stripe rust (yellow rust) and leaf rust.

Application timing, spray equipment, and resistance stewardship

Apply preventively or at the earliest sign of disease lesions using a knapsack or motorized sprayer equipped with hollow cone nozzles for thorough canopy coverage. Always follow the statutory pre-harvest interval (PHI) specified on the approved manufacturer label before harvest. To prevent fungal resistance build-up, limit applications to a maximum of two sprays per season and rotate with alternative FRAC mode of action fungicides.

Official source

Check the latest rules, benefits and forms here. KisanPe is an independent platform and is not a government website.

Central Insecticides Board and Registration Committee ↗

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Common questions

What are the two active fungicide classes in Azoxystrobin + Difenoconazole SC?

It combines a strobilurin (Azoxystrobin, FRAC Group 11) and a triazole (Difenoconazole, FRAC Group 3).

How does the dual-action formula provide both preventative and curative control?

Azoxystrobin prevents spore germination on the leaf surface, while Difenoconazole penetrates inside plant tissue to eradicate existing fungal mycelium.

Why is this premix considered effective for fungicide resistance management?

The fungus must overcome two completely distinct biochemical modes of action simultaneously, which drastically reduces the probability of resistant strains emerging.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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