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Crop Protection & Pesticides

Chlorpyriphos 50% + Cypermethrin 5% EC Guide

Chlorpyriphos 50% + Cypermethrin 5% EC is a broad-spectrum combination insecticide that unites an organophosphate with a synthetic pyrethroid to deliver quick knockdown and residual control of destructive pests. By combining acetylcholinesterase inhibition with voltage-gated sodium channel disruption, it overpowers complex infestations of chewing and sucking insects simultaneously. Widely used in cotton and commercial vegetables, applicators must follow strict label dosages and maintain personal protective gear.

Last reviewed: 10 November 2026

Dual Chemical Chemistry and Mode of Action

This premix combines two distinct neurotoxic modes of action to prevent pest resistance.

Key biochemical attributes:

  • Chlorpyriphos (50%): Organophosphate that inhibits acetylcholinesterase, causing acetylcholine accumulation and continuous nerve excitation.
  • Cypermethrin (5%): Synthetic pyrethroid that delays closure of sodium channels, delivering rapid 'knockdown' paralysis on target pests.
  • Four-way exposure action: Provides contact, stomach, respiratory vapor, and repellent activity against target insects.
  • Overcoming tolerance: The synergistic combination delivers effective control against borer populations that show tolerance to single molecules.

Target Crops and Insect Complex Controlled

The combination is registered under CIBRC guidelines for severe mixed pest attacks.

Major registered crop uses:

  • Cotton: Controls complex bollworm infestations (American bollworm, spotted bollworm, pink bollworm) along with sucking jassids and whiteflies.
  • Vegetables (Tomato, Brinjal, Chilli): Manages fruit and shoot borers, leaf miners, and chewing cutworms.
  • Paddy (Rice): Applied in specialized schedules to control yellow stem borer and leaf folder outbreaks.
  • Soil pest management: Suppresses soil cutworms and root-feeding insects when applied per label instructions.

Safe Handling, Mixing and Harvest Intervals

Due to high biological potency, applicators must adhere to strict safety measures during spray preparation.

Operational precautions:

  • Strict label dosage: Measure precisely according to official package instructions; mix using clean water and hollow cone nozzles.
  • Avoid water bodies: Highly toxic to fish and aquatic life; never rinse spray tanks or dispose of residues in irrigation canals or farm ponds.
  • Personal protective equipment: Wear chemical-resistant rubber boots, nitrile gloves, safety goggles, and a vapor respirator.
  • Pre-harvest intervals: Observe specified pre-harvest waiting periods (PHI) to prevent chemical residues on harvested crops.

Official source

Check the latest rules, benefits and forms here. KisanPe is an independent platform and is not a government website.

Directorate of Plant Protection, Quarantine & Storage ↗

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Common questions

What active ingredients are in Chlorpyriphos 50% + Cypermethrin 5% EC?

It contains Chlorpyriphos (50%), an organophosphate, and Cypermethrin (5%), a synthetic pyrethroid, in an emulsifiable concentrate formulation.

Why is this combination insecticide popular for cotton farming?

It combines rapid knockdown with long residual control, effectively managing both resistant bollworm complexes and sucking pests in one pass.

Can this chemical be sprayed near aquaculture ponds?

No, it is highly toxic to fish and aquatic organisms; spray drift or wash water must never enter canals or fish ponds.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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