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Crop Protection & Pesticides

Chlorpyrifos 50% EC: Target Pests, Safety, and Label Precautions

Chlorpyrifos 50% EC is a concentrated organophosphate insecticide designed for agricultural pest control against termites, stem borers, and soil pests. It works via contact, stomach, and vapor action per label directions registered under the Central Insecticides Board.

Last reviewed: 10 November 2026

Chemical Mode of Action and Pest Spectrum

Chlorpyrifos (IRAC Group 1B) acts as a potent inhibitor of the acetylcholinesterase (AChE) enzyme in the insect nervous system. The resultant accumulation of acetylcholine leads to neuroexcitation, tremors, and insect mortality.

Its high vapor pressure allows it to penetrate soil voids and reach concealed pests effectively.

  • Soil application: Highly effective for termite management in timber structures, sugarcane furrows, and agricultural field beds.
  • Foliar application: Controls bollworms and sucking pests in cotton within authorized CIBRC registration parameters.
  • Vapor action: Possesses significant vapor pressure that aids in flushing insects out of hidden cracks, crevices, and underground tunnels.

Safe Handling, Buffer Zones, and Regulatory Norms

Due to high toxicity to aquatic organisms and mammals, Chlorpyrifos requires strict safety protocols during application. Applicators must maintain safety buffer zones away from water bodies.

Adhering to authorized crop uses prevents illegal chemical residue accumulation in commercial food chains.

  • Wear impermeable nitrile gloves, protective footwear, chemical goggles, and an organic vapor respirator during handling.
  • Strictly respect pre-harvest intervals (PHI) to avoid chemical residue non-compliance in harvested produce.
  • Do not apply during bloom periods or near apiaries to protect foraging pollinators.

Official source

Check the latest rules, benefits and forms here. KisanPe is an independent platform and is not a government website.

Central Insecticides Board & Registration Committee ↗

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Common questions

What is the active ingredient in Chlorpyrifos 50% EC?

It contains Chlorpyrifos at 50% concentration in an emulsifiable concentrate (EC) formulation, belonging to the organophosphate chemical class.

How is Chlorpyrifos used for termite control?

It is diluted in water and drenched into the soil around foundation trenches or applied along crop furrows to create a chemical termite barrier.

Is Chlorpyrifos safe for application on vegetable crops?

Applicators must strictly follow CIBRC label clearances; non-approved vegetable applications carry severe residue risks and may violate regulatory restrictions.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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