Technical chemical identity and ryanodine receptor mechanism
Chlorantraniliprole (common abbreviation Rynaxypyr) operates via a unique neuromuscular mode of action with high insect selectivity.
- Active chemical name: Chlorantraniliprole 18.5% w/w SC (equivalent to 200 g/L).
- Chemical classification: Anthranilic diamide group, categorized under IRAC Group 28.
- Mode of action: Activates insect ryanodine receptors (RyRs), causing continuous release of intracellular calcium from muscle sarcoplasmic reticulum.
- Physiological effect: Target larvae suffer immediate muscle contraction, lethargy, paralysis, and rapid cessation of feeding within minutes.
Registered crops and target pest spectrum in India
Coragen is approved under CIBRC registration across major staple and cash crops for managing destructive lepidopteran caterpillars.
- Rice (Paddy): Long-lasting control of yellow stem borer (Scirpophaga incertulas) and rice leaf folder.
- Sugarcane: Early shoot borer (Chilo infuscatellus) and top borer control applied during planting or early tillering.
- Cotton: Control of American bollworm, spotted bollworm, and Spodoptera caterpillars.
- Tomato and Cabbage: Fruit borer (Helicoverpa armigera) and diamondback moth (Plutella xylostella).
- Maize: Highly effective against fall armyworm (Spodoptera frugiperda) infesting the crop whorl.
Safety profile toward beneficials and IPM compatibility
Because insect ryanodine receptors differ structurally from mammalian receptors, Chlorantraniliprole offers an exceptional mammalian safety profile (green hazard triangle). It exhibits minimal toxicity toward beneficial predatory spiders, lacewings, ladybird beetles, and foraging honeybees when dry, making it an anchor molecule in sustainable IPM frameworks.
Official source
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Central Insecticides Board and Registration Committee ↗Related on KisanPe
Common questions
What is the technical chemical name of Coragen insecticide?
Coragen contains Chlorantraniliprole 18.5% SC (w/w), an anthranilic diamide insecticide.
How does Chlorantraniliprole stop caterpillar damage so quickly?
It binds to insect ryanodine receptors, releasing internal calcium and causing immediate muscle paralysis so larvae stop feeding within minutes.
Is Coragen safe for beneficial predatory insects in fields?
Yes, Chlorantraniliprole has high selectivity toward chewing caterpillar pests and shows very low toxicity toward beneficial predators and honeybees.
General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.
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