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General Agriculture & Tools

Cymoxanil + Mancozeb: Downy Mildew, Late Blight and Dose Guide

Cymoxanil 8% + Mancozeb 64% WP (popularly marketed as Curzate) is a proven combination fungicide combining a local systemic penetrant with a multi-site contact protectant. It is widely used in Indian agriculture for controlling destructive Oomycete fungal diseases like late blight in potato and downy mildew in grapes.

Last reviewed: 10 November 2026

Chemical composition and dual synergistic action

  • Cymoxanil (8%): Local systemic aliphatic nitrogen compound (FRAC Group 27 / unknown multi-site); penetrates rapidly into leaf tissue, halting fungal mycelial growth within a 24 to 48-hour curative window.
  • Mancozeb (64%): Multi-site dithiocarbamate protectant (FRAC Group M03); forms a broad-spectrum protective chemical barrier on the leaf surface, preventing spore germination.
  • Kickback curative action: Cymoxanil offers 1 to 2 days of curative action after infection, arresting early incubational fungal development.
  • Anti-resistance durability: Combining a penetrant with multi-site contact Mancozeb ensures zero risk of pathogen resistance.

CIBRC approved target crops and diseases

Approved under CIBRC label directions for managing Late blight (Phytophthora infestans) in potato and tomato; and Downy mildew (Plasmopara viticola) in grapes. In potato cultivation during cool, overcast winter periods, spraying this combination arrests disease spread and protects developing tubers from fungal rot.

Application guidelines, dosage and safety

  • Standard label dosage is typically 600 to 750 grams per acre diluted in 200 liters of water for field crops.
  • Apply preventively or at the earliest appearance of water-soaked foliar lesions using a hollow cone nozzle.
  • Ensure complete coverage of both upper and lower leaf surfaces; rain-fast within 2 to 3 hours of application.
  • Observe the mandatory Pre-Harvest Interval (PHI) specified on the container before harvesting edible produce.

Official source

Check the latest rules, benefits and forms here. KisanPe is an independent platform and is not a government website.

Directorate of Plant Protection, Quarantine & Storage (CIBRC) ↗

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Common questions

What are the active chemical ingredients in Cymoxanil + Mancozeb WP?

It contains Cymoxanil 8% + Mancozeb 64% formulated as a Wettable Powder (WP).

What is the 'kickback' action of Cymoxanil?

Cymoxanil possesses a 24 to 48-hour curative window, meaning it can cure internal fungal infections if sprayed within 1 to 2 days after spore penetration.

Which major plant diseases does this fungicide combination control?

It is highly effective against Late blight in potato and tomato, and Downy mildew in grapes and cucurbits.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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