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Crop Protection & Pesticides

Difenoconazole 25 EC Fungicide: Score Crop Disease Guide

Difenoconazole 25 percent EC is a broad-spectrum systemic triazole fungicide used to control powdery mildew, scab, rust, anthracnose, and leaf spot complexes. It translocates acropetally through plant xylem to inhibit fungal ergosterol biosynthesis, providing preventive, curative, and eradicative disease control.

Last reviewed: 11 November 2026

Active Ingredient Profile and Triazole Mode of Action

Difenoconazole belongs to the triazole/demethylation inhibitor (DMI) chemical class (FRAC Group 3).

It acts by inhibiting the 14-alpha demethylase enzyme required for fungal ergosterol biosynthesis.

Deprived of functional ergosterol, fungal cell membranes lose integrity, causing cytoplasmic leakage and arresting hyphal elongation and appressorial penetration.

  • Formulation: 25 percent Emulsifiable Concentrate (EC)
  • Systemic xylem movement: Rapidly absorbed by foliage and translocated upward toward expanding new shoots
  • Triazole curative power: Provides curative therapy against incubating fungal infections within the host tissue

Target Crop Diseases and Approved Registrations

Difenoconazole is registered across apple, grapevine, chili, paddy, peanut, and vegetable crops.

It is recognized as a premier solution for apple scab, grape powdery mildew, and chili anthracnose dieback.

Its translaminar and systemic mobility protects foliage, blossoms, and developing fruit clusters simultaneously.

  • Apple: Primary curative and preventive protectant against apple scab (Venturia inaequalis)
  • Chilies: Controls fruit rot (anthracnose) and dieback caused by Colletotrichum species
  • Paddy: Manages sheath blight and grain discoloration complexes during reproductive phases

Application Guidelines, Mixing, and Resistance Stewardship

Apply preventively at early vegetative flush or during early disease onset before lesions multiply.

Dilute the emulsifiable concentrate in clean water with continuous agitation and apply using fine mist sprayers.

Rotate with multi-site contact protectants like Mancozeb to maintain long-term chemical efficacy.

  • Spray timing: Apply during cool morning or evening hours with high-volume knapsack sprayers
  • Rainfastness: Rapid absorption into leaf waxes provides dependable rain resistance within two hours
  • Resistance rotation: Rotate with contact protectants or strobilurins across the cropping season

Official source

Check the latest rules, benefits and forms here. KisanPe is an independent platform and is not a government website.

Central Insecticides Board & Registration Committee ↗

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Common questions

What is Difenoconazole 25 EC primarily used for?

It is a systemic triazole fungicide used to prevent and cure diseases like apple scab, powdery mildew, anthracnose, and leaf spots.

Does Difenoconazole have curative action inside the leaf?

Yes, its systemic vascular mobility enables it to penetrate plant tissues and cure early incubating fungal infections.

Can Difenoconazole be combined with contact protectants?

Yes, it is frequently combined or rotated with multi-site contact protectants like Mancozeb or Copper Oxychloride to prevent resistance.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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