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Crop Protection & Pesticides

Hexaconazole Fungicide: Mode of Action, Diseases and Usage

Hexaconazole is a widely used systemic triazole fungicide available in formulations such as 5% SC and 5% EC for controlling powdery mildews, blights, and rusts. It acts systemically through acropetal translocation, inhibiting fungal ergosterol biosynthesis to halt infection spread within plant tissues.

Last reviewed: 10 November 2026

Chemical profile and mode of action

  • Belongs to the triazole chemical group, categorized under FRAC Group 3 (Demethylation Inhibitors - DMI).
  • Inhibits the 14-alpha-demethylase enzyme in fungal sterol pathways, preventing the synthesis of ergosterol required for fungal cell walls.
  • Provides protective, curative, and eradicant action with rapid xylem translocation toward new leaf tips.

Target fungal diseases and crop spectrum

  • Paddy: Exceptional curative and preventive control of sheath blight (Rhizoctonia solani).
  • Grapes and mango: Controls powdery mildew (Uncinula necator and Oidium mangiferae) on leaves and flowering panicles.
  • Groundnut: Suppresses tikka leaf spot (Cercospora arachidicola) and rust diseases.
  • Apple: Controls apple scab and powdery mildew in temperate fruit orchards.

Application guidelines and resistance stewardship

  • Apply at the first appearance of disease symptoms using a calibrated knapsack or power sprayer with hollow-cone nozzles.
  • Rotate with non-DMI fungicides (such as strobilurins or multi-site contact fungicides) to avoid developing resistant fungal strains.
  • Strictly observe CIBRC registered label dosages, pre-harvest intervals, and personal safety protocols.

Official source

Check the latest rules, benefits and forms here. KisanPe is an independent platform and is not a government website.

Central Insecticides Board & Registration Committee (CIBRC) ↗

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Common questions

What is the mode of action of Hexaconazole?

It is a triazole systemic fungicide that inhibits fungal ergosterol cell membrane biosynthesis.

Which major disease does Hexaconazole control in rice?

It is widely used to control sheath blight (Rhizoctonia solani) in paddy crops.

Is Hexaconazole effective against powdery mildew?

Yes, it provides excellent curative and preventive control of powdery mildew in grapes, mango, and vegetables.

How is Hexaconazole absorbed by the plant?

It is rapidly absorbed through green foliage and translocated upward through the plant's xylem vascular system.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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