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Crop Protection & Pesticides

Incipio Syngenta Technical Name: Isocycloseram SC

The technical name of Incipio by Syngenta is isocycloseram 18.18% w/w SC, belonging to the novel isoxazoline chemical class powered by PLINAZOLIN technology. It functions as a GABA-gated chloride channel antagonist that provides long-lasting, resistance-breaking control against yellow stem borer and leaf folder in paddy. Its rapid rainfastness, broad-spectrum efficacy, and distinct biochemical target make it a powerful crop protection tool against stem borers tolerant to older chemistries.

Last reviewed: 10 November 2026

Technical Identity and Chemical Characteristics

Incipio introduces an innovative mode of action within the insecticide landscape.

Key technical specifications:

  • Technical active: Isocycloseram formulated as a suspension concentrate at 18.18% w/w SC concentration.
  • Chemical family: Isoxazoline class (PLINAZOLIN technology / IRAC Group 30).
  • GABA receptor antagonist: Binds selectively to GABA-gated chloride channels, causing hyper-excitation, convulsions, and termination of target insect pests.
  • Overcoming resistance: Exhibits no cross-resistance with diamides, organophosphates, or pyrethroids, providing effective control against resistant stem borer strains.

Target Crop and Rice Pest Spectrum

Incipio is specifically engineered to protect paddy crops during critical vegetative and tillering phases.

Major registered rice pests:

  • Yellow stem borer (Scirpophaga incertulas): Controls borer larvae, preventing dead heart during vegetative growth and white head during reproductive stages.
  • Leaf folder (Cnaphalocrocis medinalis): Stops larvae from rolling leaves and scraping green chlorophyll, keeping leaf canopies intact for grain filling.
  • Extended residual control: Delivers sustained pest protection for multiple weeks, reducing the number of seasonal spray passes required.

Application Guidelines and Spray Safety

Applying Incipio at approved crop windows ensures maximum translaminar uptake.

Safe spraying practices:

  • Application timing: Apply at early borer egg hatch or first visible dead heart symptoms, typically between 20 and 45 days after transplanting.
  • Rainfastness: Penetrates leaf wax and becomes rainfast within one hour, ensuring reliable field efficacy during monsoon rainfall.
  • Dosage compliance: Measure strictly according to package instructions using clean water and hollow cone nozzles.
  • Protective gear: Wear personal protective equipment including rubber gloves, eye goggles, and a face shield during mixing.

Official source

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Directorate of Plant Protection, Quarantine & Storage ↗

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Common questions

What is the technical chemical name of Incipio by Syngenta?

The technical name of Incipio is Isocycloseram 18.18% w/w SC, belonging to the isoxazoline chemical class.

How does isocycloseram eliminate yellow stem borers in paddy?

It acts as a GABA-gated chloride channel antagonist, disrupting insect nervous system transmission and terminating borer larvae.

Does Incipio control pests that are resistant to older diamide insecticides?

Yes, because it operates on a novel IRAC Group 30 target site, it controls borer populations that have developed tolerance to diamides.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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