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Crop Protection & Pesticides

M-45 Fungicide Uses: Mancozeb 75 WP Disease Guide

M-45 fungicide is a broad-spectrum contact protectant containing Mancozeb 75 percent WP used to control blight, downy mildew, leaf spot, and rust across major field and horticultural crops. It creates a multi-site protective barrier on plant foliage that inhibits fungal spore germination.

Last reviewed: 11 November 2026

Active Ingredient and Protective Mode of Action

M-45 contains Mancozeb, a coordination product of zinc ion and manganese ethylene bisdithiocarbamate.

As a multi-site protective fungicide, it disrupts lipid metabolism, respiration, and ATP synthesis across multiple biochemical pathways in target fungal spores.

Because of this broad multi-site inhibition, fungal pathogens do not easily develop chemical resistance against Mancozeb.

  • Formulation: 75 percent Wettable Powder (WP)
  • Protective action: Multi-site surface contact fungicide preventing spore germination and penetration
  • Secondary nutrients: Supplies trace amounts of manganese and zinc nutrients to foliage

Major Crop Diseases Controlled by M-45

M-45 is registered across numerous crops including potato, tomato, paddy, wheat, chili, and grapevine.

Applications must be timed preventively ahead of rainy weather or immediately upon noticing early foliar lesions.

  • Potato and tomato: Controls early blight (Alternaria solani) and late blight (Phytophthora infestans)
  • Paddy: Suppresses blast (Pyricularia oryzae) and brown spot (Helminthosporium oryzae)
  • Horticulture: Controls anthracnose, downy mildew, and rust across vegetables and fruits

Spraying Instructions, Slurry Mixing, and Safety

Always prepare a smooth pre-slurry in a separate container of water before adding to the main spray tank to ensure complete powder suspension.

Maintain continuous tank agitation during spraying and observe recommended pre-harvest intervals before food crop harvest.

  • Mixing: Avoid dumping dry powder directly into a full sprayer tank to prevent lump formation
  • Uniform coverage: Spray both upper and lower canopy surfaces until leaves are evenly coated
  • Personal protection: Wear chemical-resistant gloves, dust mask, and eye goggles during handling

Official source

Check the latest rules, benefits and forms here. KisanPe is an independent platform and is not a government website.

Central Insecticides Board & Registration Committee ↗

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Common questions

What is the active chemical in M-45 fungicide?

M-45 contains Mancozeb 75% WP, a broad-spectrum contact dithiocarbamate fungicide.

Does M-45 cure established fungal infections inside the plant?

No, M-45 is a contact protectant; it prevents new spores from infecting but does not translocate systemically inside plant tissues.

Can M-45 be tank-mixed with insecticides?

Yes, M-45 is compatible with most non-alkaline insecticides, though a preliminary jar compatibility test is always recommended.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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