Chemical properties and neurotoxic mode of action
Monocrotophos is a fast-acting organophosphate compound possessing both contact and systemic properties with high water solubility.
It works by irreversibly inhibiting the acetylcholinesterase (AChE) enzyme at insect nerve synapses. This causes accumulation of acetylcholine, leading to continuous neural overstimulation, muscle spasms, convulsions, and death.
- Active chemical: Monocrotophos 36% SL (soluble liquid).
- Chemical class: Organophosphate (Acetylcholinesterase enzyme inhibitor).
- Systemic penetration: Rapidly absorbed by plant tissues, providing translaminar and acropetal translocation to protect expanding vegetative parts.
Approved crops and statutory ban on vegetable crops
Because of its high acute toxicity and persistent residues, the Government of India and the Central Insecticides Board & Registration Committee (CIBRC) have enacted strict regulatory restrictions on Monocrotophos.
It is strictly prohibited by law from being applied on any vegetable crops. Use is restricted exclusively to approved non-vegetable crops.
- STRICT BAN ON VEGETABLES: Absolutely prohibited on all vegetables (tomato, brinjal, chilli, okra, cabbage, cauliflower, cucurbits).
- Approved non-vegetable crops: Registered for bollworms and sucking pests in cotton, and specific pests in pulses, oilseeds, and plantation crops.
- Paddy (Rice): Registered for yellow stem borer, leaf folder, and gall midge control.
- Cardamom & Coffee: Specific borer and sucking pest management under strict label protocols.
High toxicity hazards, antidote, and handling safety
Monocrotophos is classified under the high-hazard red/yellow chemical toxicity category with severe acute toxicity upon oral, dermal, or inhalation exposure.
Applicators must wear full personal protective equipment, avoid spraying near water bodies, and keep the physiological antidote (Atropine sulphate) accessible under qualified medical care.
- Medical antidote: Atropine sulphate, along with 2-PAM (Pralidoxime), administered strictly under qualified medical emergency supervision.
- Protective equipment: Mandatory use of chemical-resistant overalls, rubber gloves, vapor respirator mask, and protective goggles.
- Pre-harvest interval: Strictly respect statutory pre-harvest intervals (PHI) to prevent illegal chemical residues in harvested agricultural produce.
Official source
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Central Insecticides Board & Registration Committee ↗Related on KisanPe
Common questions
Is Monocrotophos legally permitted on vegetable crops in India?
No, Monocrotophos is strictly prohibited by government regulations from being applied on any vegetable crops due to severe residue hazards.
What is the mode of action of Monocrotophos insecticide?
It inhibits the acetylcholinesterase enzyme in insect nervous systems, causing continuous excitation, paralysis, and death.
What is the medical antidote for organophosphate poisoning?
Atropine sulphate administered under emergency hospital supervision serves as the specific physiological antidote.
General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.
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