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Crop Protection & Pesticides

Profenofos 50% EC Insecticide: Pests, Mode and Safety

Profenofos 50% EC is a broad-spectrum organophosphate insecticide and acaricide registered under CIBRC for agricultural pest control. Renowned for its rapid translaminar leaf penetration, ovicidal efficacy, and contact toxicity, it provides powerful suppression of chewing caterpillars, bollworms, and foliar mites across cotton, soybean, and vegetable crops.

Last reviewed: 10 November 2026

Active ingredient and biochemical mode of action

Profenofos is an organothiophosphate insecticide classified under IRAC Group 1B. It functions as an irreversible inhibitor of the acetylcholinesterase (AChE) enzyme in insect synapses, leading to toxic acetylcholine build-up, neuromuscular convulsions, and death. It exhibits strong translaminar mobility, penetrating into leaf mesophyll tissues.

  • Active constituent: Profenofos 50% EC (emulsifiable concentrate)
  • Chemical class: Organophosphate (IRAC Group 1B)
  • Ovicidal action: Penetrates insect eggshells, killing developing embryos before hatching

Target crops and major pest complexes

  • Cotton: American bollworm (Helicoverpa armigera), spotted bollworm, and whitefly nymphs.
  • Soybean: Semilooper, tobacco caterpillar (Spodoptera litura), and girdle beetle.
  • Vegetables: Fruit borer in tomato, diamondback moth in cabbage, and red spider mites.

Application precautions and personal safety

Organophosphates demand rigorous safety compliance. Always wear complete personal protective equipment including chemical-resistant gloves, respirators, eye goggles, and full-body clothing. Never spray against wind direction or near fish ponds. Adhere strictly to CIBRC approved label dosages and pre-harvest intervals.

Official source

Check the latest rules, benefits and forms here. KisanPe is an independent platform and is not a government website.

Central Insecticides Board & Registration Committee ↗

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Common questions

What is the chemical class of Profenofos 50% EC?

It belongs to the organophosphate chemical class (IRAC Group 1B), acting as an acetylcholinesterase inhibitor.

Does Profenofos 50% EC possess ovicidal activity?

Yes, it has strong ovicidal properties, penetrating pest egg masses to kill embryos before they hatch into feeding larvae.

What is the medical antidote for organophosphate insecticide exposure?

Atropine sulphate accompanied by pralidoxime (PAM) administered promptly under medical supervision is the specific antidote.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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