Skip to content
KisanPe
Crop Protection & Pesticides

Profenofos + Cypermethrin: Active Ingredients and Pests

Profenofos 40% + Cypermethrin 4% EC is a widely registered combination insecticide formulation that provides broad-spectrum pest management in commercial crops. By combining an organophosphate with a synthetic pyrethroid, it delivers rapid knockdown, translaminar action, and residual efficacy against chewing and sucking insect complexes.

Last reviewed: 10 November 2026

Mode of action and chemical synergy

The two active ingredients operate through distinct biochemical pathways. Profenofos inhibits acetylcholinesterase in the insect central nervous system, while Cypermethrin keeps sodium channels open in nerve membranes. This dual action disrupts neurotransmission, delivering ovicidal, larvicidal, and adulticidal mortality.

  • Profenofos (40%): Organophosphate insecticide with translaminar penetration and strong ovicidal action.
  • Cypermethrin (4%): Type-II synthetic pyrethroid delivering quick knock-down upon contact or ingestion.
  • Formulation: Emulsifiable Concentrate (EC) for uniform foliar coverage.

Target crops and major insect pests

  • Cotton: American bollworm (Helicoverpa armigera), spotted bollworm, and sucking pests like whiteflies and aphids.
  • Soybean: Semilooper, girdle beetle, and tobacco caterpillar.
  • Vegetables: Fruit and shoot borer in brinjal, fruit borer in tomato, and diamondback moth in cole crops.

Safe handling and label directions

Spray when pest populations cross economic threshold levels (ETL) using standard personal protective equipment. Never apply during peak honeybee foraging hours or windy conditions. Strictly observe the CIBRC approved pre-harvest interval (PHI) before picking crops.

Official source

Check the latest rules, benefits and forms here. KisanPe is an independent platform and is not a government website.

Central Insecticides Board & Registration Committee ↗

Related on KisanPe

Common questions

What is the formulation of Profenofos and Cypermethrin?

It is formulated as an emulsifiable concentrate containing 40% Profenofos and 4% Cypermethrin by weight.

Does this combination insecticide kill pest eggs?

Yes, Profenofos exhibits notable ovicidal action, preventing pest eggs from hatching on foliage.

Why is protective gear essential when spraying organophosphates?

Organophosphates can be absorbed through skin and inhalation, requiring gloves, eye protection, and masks during preparation and spraying.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

More Crop Protection & Pesticides guides

Ask Sakhi AI in your language, check live mandi prices or plan a loan with KisanPe tools.

Ask Sakhi
Download KisanPe App