Chemical Class and Synergistic Modes of Action
Profiler combines two powerful active ingredients: Fluopicolide belongs to the acylpicolide chemical class (FRAC Group 43), which acts by disrupting spectrin-like proteins in fungal cell architecture, causing rapid cell membrane destabilization and zoospore bursting.
Fosetyl-Al belongs to the phosphonate group (FRAC Group 33), offering two-way ambimobile systemic translocation through both xylem and phloem, directly suppressing fungal hyphae while triggering the plant's systemic acquired resistance (SAR). Together, they deliver immediate and prolonged protection.
- Novel Acylpicolide Chemistry: Fluopicolide disrupts spectrin-like proteins, causing rapid zoospore lysis.
- Ambimobile Systemic Translocation: Fosetyl-Al moves upward and downward to protect newly emerging shoots and bunches.
- Water Dispersible Granules (WG): Dust-free granules that dissolve rapidly in water without nozzle clogging.
Target Disease: Downy Mildew in Grapes
Downy mildew caused by Plasmopara viticola is the most destructive disease affecting commercial grape vineyards in India. High humidity, rain, and cool nights trigger oil-spot lesions on leaves and white downy growth that destroys flowering clusters and berries.
Profiler is officially registered under CIBRC standards for controlling grape downy mildew. Applying Profiler during pre-bloom, flowering, and berry setting shields delicate fruit bunches and preserves photosynthetic canopy area.
- Bunch Protection: Shields tender flower clusters and berries from downy mildew infections.
- Oil-Spot Eradication: Arrests active oil-spot lesions and suppresses secondary sporulation on leaf undersides.
- Translaminar Movement: Quickly penetrates leaf cuticles, offering strong rainfast protection within hours.
Application Guidelines and Resistance Stewardship
Apply Profiler preventively at the onset of weather conditions favorable to downy mildew or at the very first visual indication of oil spots. Maintain adequate spray volume using motorized vineyard blowers or power sprayers.
To prevent pathogen resistance, avoid more than two to three applications of Profiler per season, and rotate with fungicides of different modes of action (such as Mandipropamid, Dimethomorph, or multisite copper protectants).
- Optimal Timing: Spray at 3 to 5 leaf stage, pre-bloom, or post-bloom berry set for maximum cluster defense.
- Water Volume: Ensure complete canopy coverage to coat both upper and lower leaf surfaces.
- Pre-Harvest Interval (PHI): Observe recommended harvest waiting windows as prescribed on the product label.
Official source
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Central Insecticides Board & Registration Committee (CIBRC) ↗Related on KisanPe
Common questions
What is the technical composition of Profiler fungicide?
Profiler contains Fluopicolide 4.44% + Fosetyl-Al 66.67% WG (Water Dispersible Granules), manufactured by Bayer.
Which major disease does Profiler control in grapes?
It specifically manages grape downy mildew caused by Plasmopara viticola.
How does Fluopicolide in Profiler destroy fungal zoospores?
It disorganizes spectrin-like proteins in the fungal cell structure, causing the cell membrane to rupture and zoospores to burst within minutes.
General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.
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