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Crop Protection & Pesticides

Sefina Insecticide: BASF Afidopyropen Whitefly Guide

Sefina is an innovative selective insecticide manufactured by BASF, powered by Inscalis technology (afidopyropen 50 g/L DC). Specifically engineered for whiteflies, aphids, and jassids in cotton and vegetable crops, Sefina targets chordotonal stretch receptors to halt insect sap-feeding within minutes while maintaining an exceptional safety profile for honeybees.

Last reviewed: 11 November 2026

Active Ingredient and Inscalis Mode of Action

Afidopyropen represents a novel pyropene chemical class derived from the fermentation of the fungus Penicillium coprobium.

Classified under IRAC Group 9D, it targets vanilloid receptor-like (TRPV) channels in chordotonal organs, disrupting the insect's senses of hearing, balance, and gravity, which induces immediate and irreversible feeding cessation.

  • Active Molecule: Afidopyropen 50 g/L DC (Dispersible Concentrate)
  • Inscalis Technology: Chordotonal organ modulator paralyzing the sensory and feeding organs of sucking pests
  • Rapid Feeding Cessation: Target sucking insects stop extracting plant sap within minutes of contact, preventing viral transmission
  • Acro-Translaminar Movement: Penetrates leaf tissues, moving acropetally to protect newly expanding leaves and shoots

Target Pests and Crop Defense

Sefina is registered across broad-acre fiber crops and high-value vegetables facing destructive homopteran pest attacks.

In cotton, it provides knockdown and long-lasting residual control of all whitefly life stages (nymphs and adults).

  • Cotton: Whiteflies (Bemisia tabaci) and jassids (Amrasca biguttula biguttula)
  • Chilli: Foliar aphids and whitefly complexes causing honeydew sooty mold
  • Brinjal & Tomato: Whiteflies and jassids transmitting geminiviruses
  • Extended Protection: Delivers up to 14 to 21 days of persistent sucking pest suppression

Application Guidelines and Pollinator Safety

Sefina offers an outstanding safety profile toward honeybees, predatory ladybird beetles, and lacewings, making it an ideal IPM tool.

Apply at the first appearance of whitefly nymphs using hollow-cone nozzles for thorough canopy penetration.

  • Application Rate: Apply at 400 ml per acre using 200 liters of water for complete vegetative coverage
  • Timing: Early intervention at threshold levels prevents whitefly population explosions and honeydew mold
  • Beneficial Conservation: Highly selective; preserves natural predators that consume remaining pest populations

Official source

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Central Insecticides Board & Registration Committee ↗

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Common questions

What is the technical chemistry in BASF Sefina?

Sefina contains afidopyropen (Inscalis technology) 50 g/L DC, a novel pyropene chordotonal organ modulator.

How fast does Sefina stop whitefly damage?

Afidopyropen stops whitefly feeding within minutes of ingestion or contact, halting plant damage and virus transmission.

Is Sefina safe for honeybees and predatory insects?

Yes, Sefina has an exceptional safety profile toward honeybees and beneficial predators, making it suitable for Integrated Pest Management.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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