Active chemical class and Plinazolin technology
Simodis contains Isocycloseram (Plinazolin active), an innovative compound pioneering the isoxazoline class of GABA-gated chloride channel antagonists (IRAC Group 30).
It works by binding to a completely novel allosteric site on GABA-gated chloride channels in insect nerve synapses. By blocking inhibitory signals, it causes continuous neuromuscular hyperexcitation, paralysis, immediate feeding cessation, and rapid mortality.
- Active chemical: Isocycloseram 10% w/v DC (100 g/L).
- IRAC classification: Group 30 (GABA-gated chloride channel allosteric antagonist).
- Breakthrough resistance breaker: Unmatched control over pest strains resistant to diamides, organophosphates, and pyrethroids.
Target crops and approved multi-pest spectrum
Simodis is registered in India for managing devastating complexes of chewing caterpillars, thrips, and mites across high-value horticultural and field crops.
It is celebrated for providing dual control of hard-to-kill thrips and fruit borers in chilli and vegetable farming.
- Chilli: Black thrips (Thrips parvispinus), yellow mites, and fruit borer (Helicoverpa armigera).
- Tomato: Fruit borer, pinworm, and thrips.
- Brinjal: Shoot and fruit borer (Leucinodes orbonalis).
- Cabbage & Cauliflower: Diamondback moth (Plutella xylostella) and cluster caterpillar.
Application timing, foliar coverage, and safety
Apply Simodis at the early onset of pest infestation or when black thrips first appear on flower buds and young foliage.
Its dispersible concentrate formulation mixes smoothly with clean water and provides excellent UV stability and rainfastness within 2 hours of drying.
Observe personal protective equipment protocols and adhere to container label directions during preparation and application.
- Spraying technique: Ensure uniform canopy wetting using fine hollow cone nozzles operated at label-prescribed dilutions.
- Sunlight stability: Demonstrates outstanding stability under high UV radiation and extreme summer temperatures.
- Protective measures: Wear protective eyewear, chemical-resistant gloves, and face shield; respect statutory pre-harvest intervals.
Official source
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Central Insecticides Board & Registration Committee ↗Related on KisanPe
Common questions
What is the active ingredient in Syngenta Simodis?
Simodis contains Isocycloseram 10% w/v DC, powered by Plinazolin technology (IRAC Group 30).
Does Simodis effectively control black thrips (Thrips parvispinus) in chilli?
Yes, Simodis is highly effective in managing invasive black thrips as well as fruit borers and mites in chilli crops.
How does Plinazolin technology overcome chemical resistance?
It binds to a novel allosteric site on insect GABA chloride channels, bypassing existing target-site resistance to older chemical classes.
General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.
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