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Crop Protection & Pesticides

Simodis Insecticide: Isocycloseram DC Pest Control

Simodis by Syngenta is an innovative broad-spectrum insecticide formulated with isocycloseram 9.2% w/w DC (dispersible concentrate) powered by PLINAZOLIN technology. It targets GABA-gated chloride channels in insect nervous systems, delivering powerful, resistance-breaking control against difficult chewing and sucking pests. Formulated for high UV stability and rapid rainfastness, Simodis provides extended crop protection against thrips, fruit borers, and diamondback moths in vegetables and commercial crops.

Last reviewed: 10 November 2026

Active Ingredient Chemistry and Mode of Action

Simodis represents a breakthrough in insecticide innovation, introducing an entirely novel biochemical target site.

Key chemical attributes:

  • Active ingredient: Isocycloseram formulated as a dispersible concentrate at 9.2% w/w DC concentration.
  • Chemical family: Isoxazoline class (PLINAZOLIN technology / IRAC Group 30).
  • GABA receptor antagonist: Binds to GABA-gated chloride channels, causing hyper-excitation, paralysis, and rapid insect mortality.
  • Overcoming resistance: Highly effective against insect strains that have developed resistance to organophosphates, pyrethroids, and diamides.

Target Crops and Destructive Pest Complex

Simodis provides cross-spectrum control of both chewing caterpillars and elusive sucking pests.

Major registered crop uses:

  • Chilli: Controls yellow thrips (Scirtothrips dorsalis), fruit borers, and mites, keeping foliage smooth and pods blemish-free.
  • Brinjal and Tomato: Controls shoot and fruit borer (Leucinodes orbonalis), Helicoverpa fruit borer, and thrips.
  • Cabbage and Cauliflower: Effectively manages diamondback moth (DBM) larvae tolerant to conventional chemistries.
  • Cotton: Registered for managing thrips, jassids, and bollworms during vegetative and squaring stages.

Application Guidelines and Spray Safety

Proper application ensures maximum translaminar penetration through waxy vegetable cuticles.

Safe spraying guidelines:

  • Rainfastness and UV stability: Penetrates leaf cuticles rapidly, providing excellent rainfastness within one hour and resisting sunlight degradation.
  • Label dose compliance: Measure strictly per official package instructions; ensure thorough coverage of both upper and lower leaf surfaces.
  • Resistance rotation: Rotate with insecticides from alternative IRAC mode of action groups to maintain long-term field efficacy.
  • Protective equipment: Wear personal protective equipment including chemical-resistant gloves, goggles, and a face shield during mixing.

Official source

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Directorate of Plant Protection, Quarantine & Storage ↗

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Common questions

What is the active chemical ingredient in Simodis by Syngenta?

Simodis contains Isocycloseram 9.2% w/w DC, belonging to the novel isoxazoline chemical class powered by PLINAZOLIN technology.

Which major pests does Simodis control in chilli crops?

It provides exceptional control against chilli thrips, fruit borers, and pest mites in a single integrated application.

Does Simodis control pests that are resistant to older insecticides?

Yes, because isocycloseram acts on a novel IRAC Group 30 target site, it controls pests that are tolerant to older diamides and pyrethroids.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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