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Crop Protection & Pesticides

Spinosad Insecticide: Active Ingredient, Pests & Safety

Spinosad is a naturally derived fermentation insecticide (spinosyn A and spinosyn D) produced by the soil actinomycete bacterium Saccharopolyspora spinosa. Widely formulated as 45% SC and 2.5% SC, it provides broad-spectrum efficacy against caterpillars, thrips, and leaf miners, combining the safety profile of a biological input with the killing speed of a synthetic insecticide.

Last reviewed: 10 November 2026

Active constituents and novel mode of action

Spinosad binds allosterically to nicotinic acetylcholine receptors (nAChR) at a unique site distinct from neonicotinoids, classified under IRAC Group 5. It causes continuous nerve firings, muscle contractions, tremors, feeding cessation, and neuromuscular exhaustion without cross-resistance to existing organophosphate or pyrethroid chemistries.

  • Active ingredients: Spinosyn A and Spinosyn D (naturalyte class)
  • Chemical family: Spinosyns (IRAC Group 5)
  • Dual uptake: Contact and ingestion activity with excellent translaminar leaf penetration

Target crops and major insect pests

  • Chili: Yellow thrips (Scirtothrips dorsalis) and fruit borers.
  • Cotton: American bollworm, spotted bollworm, and thrips.
  • Cole crops and vegetables: Diamondback moth (Plutella xylostella) and tomato pinworm.
  • Pulses: Gram pod borer (Helicoverpa armigera).

Pollinator precautions and label directions

While spinosad has low mammalian toxicity and a favorable environmental profile, wet spray deposits are toxic to honeybees. Avoid spraying during daylight bee foraging hours. Once spray residues dry on foliage (within 3 to 4 hours), toxicity to beneficial pollinators decreases dramatically. Follow CIBRC label doses and pre-harvest intervals.

Official source

Check the latest rules, benefits and forms here. KisanPe is an independent platform and is not a government website.

Central Insecticides Board & Registration Committee ↗

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Common questions

What is the biological origin of Spinosad?

Spinosad is produced through aerobic fermentation of the naturally occurring soil actinomycete Saccharopolyspora spinosa.

Does Spinosad control thrips effectively in chili?

Yes, spinosad provides high translaminar efficacy against both flower thrips and foliage thrips in chili.

Is Spinosad toxic to beneficial honeybees?

Wet spray droplets are toxic to bees; however, dried residues are substantially safer, so spraying should only occur during evening hours.

General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.

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