Active chemical nature and mitochondrial energy shutdown
Tolfenpyrad contains 15% EC (emulsifiable concentrate), an active compound belonging to the pyrazole carboxamide chemical class (IRAC Group 21A).
It acts as an inhibitor of mitochondrial complex I in the insect and fungal respiratory chain. By blocking electron transfer from NADH to coenzyme Q, it prevents cellular ATP synthesis, causing rapid paralysis, immediate cessation of feeding, and pest mortality.
- Active chemical: Tolfenpyrad 15% EC.
- IRAC classification: Group 21A (Mitochondrial complex I electron transport inhibitor / METI).
- Triple action: Delivers insecticidal, acaricidal, and secondary fungicidal suppression in a single chemical spray.
- All-stage efficacy: Controls eggs (ovicidal), feeding nymphs, and adult pests, breaking persistent multi-generational lifecycles.
Target crops and approved multi-pest spectrum
Tolfenpyrad 15% EC is registered in India across high-value commercial vegetables, spices, and plantation crops.
It is celebrated for providing control over multi-resistant thrips complexes and diamondback moths (DBM) that evade conventional chemistries.
- Chilli: Thrips (Scirtothrips dorsalis), yellow mites, and fruit borer.
- Cabbage & Cauliflower: Diamondback moth (Plutella xylostella) and aphids.
- Cumin: Aphids and powdery mildew (Erysiphe polygoni).
- Mango: Mango hoppers and powdery mildew on flower panicles.
- Translaminar penetration: Penetrates foliar tissues rapidly to control hidden pests feeding on leaf undersides.
Application timing, foliar coverage, and safety
Apply Tolfenpyrad 15% EC upon observing early pest threshold sightings or when thrips begin infesting young growing points.
Ensure thorough and uniform canopy wetting using calibrated knapsack sprayers operated at container label recommended dilution rates.
- Spraying technique: Direct spray to cover both upper and lower leaf surfaces, shoots, and flower buds.
- Resistance management: Rotate with insecticides of different IRAC groups to preserve long-term chemical efficacy.
- Protective measures: Wear protective overalls, chemical-resistant gloves, and face shield; respect statutory pre-harvest intervals.
Official source
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Central Insecticides Board & Registration Committee ↗Related on KisanPe
Common questions
What is the active ingredient in Keefun insecticide?
Keefun contains Tolfenpyrad 15% EC, an advanced pyrazole carboxamide insecticide and acaricide.
How does Tolfenpyrad kill resistant thrips and caterpillars?
It inhibits mitochondrial complex I, shutting down cellular ATP energy generation and causing rapid feeding cessation and paralysis.
Does Tolfenpyrad have any fungicidal activity?
Yes, Tolfenpyrad exhibits secondary fungicidal activity against powdery mildew diseases in crops like cumin and mango.
General guidance, not personal advice. For your farm, ask your local Krishi Vigyan Kendra or agriculture officer.
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